Endocrine Abstracts

Objectives: The number of reported cases COVID-19 associated subacute thyroiditis (ST) in literature is small thus peculiarities of its clinical features remain the subject of interest. The aim of the review is to share our experience of COVID-19 associated ST.Materials and Methods: We describe 5 cases of COVID-19 associated ST. SARS-CoV-2 diagnosis was based on the presence of its typical symptoms and real-time polymerase chain reaction on nasopharyngea...

Background and aims: There is compelling evidence that the decline in appendicular muscle mass is a poor prognostic factor for the development of chronic complications of diabetes. In addition to chronic hyperglycemia, reduction of muscle component may be determined by metabolic disorders. Therefore, the aim of study was to assess the possible links between serum myostatin, IGF-1 and a reduction in muscle mass in type 1 diabetes mellitus (T1DM).Materials...

Background: It is known that the prevalence of skin diseases in patients with type 2 diabetes (T2D) is increased including psoriasis. Patients with T2D and psoriasis have an increased risk of psoriasis exacerbations. The study of the psoriasis manifestation features in patients with T2D can help to reduce the number of exacerbations, their severity and duration.Aims: To study the influence of T2D on the psoriasis manifestation and exacerbation. Materials...

Background: The central distribution of body fat has been identified as a significant risk factor for development of macrovascular complications in type 2 diabetes mellitus (T2D) in particular. The aim of the study was the features of fat mass distribution in T2D patients using insulin.Materials and methods: We studied 138 T2D patients with insulin in therapy (31 men and 107 women; mean age 51.43+8.41 yrs; disease duration 6.40+2.01 yrs...

Background: MEN 2b is a highly penetrant disease with an autosomal dominant pattern of inheritance. It includes medullary thyroid carcinoma, pheochromocytomas, and multiple mucosal neuromata. The common feature of all of these tumors is a neuroectodermal origin. Although the clinical phenotype is present in all patients, individual manifestations have a variable presentation and are age dependent. Aim.: We report a case of a patient with possible MEN 2b ...

Objective: Stress hyperglycemia and decreased control of diabetes mellitus are recorded in severely hospitalized patients and are associated with an increased complications level, length of hospitalization and mortality. Clinical evidence suggests an increased prevalence of hospital hyperglycemia in patients with COVID-19 and a difference from typical stress hyperglycemia.Materials and methods: We studied 219 moderate and severe hospitalized COVID-19 pat...

To analyze the data of relatives of first-degree patients operated on for medullary thyroid cancer (MTC), we analyzed the anamnestic data of the database of patients with MTC, formed on the basis of the cancer registry of the Republic of Belarus and medical records of the Republican Thyroid Tumor Center. Further examination of relatives is also performed on the basis of the Republican Center for Thyroid Tumors.The aim: of the study was to create a databa...

Assessment of basal calcitonin as the main marker of medullary thyroid cancer (MTC) was introduced into routine practice in the Republic of Belarus more than 10 years ago. A number of laboratory and clinical factors can influence the result of this parameter determination. Equally important is the gender, age, weight, the deviation of the serum calcium level, certain medications.The aim: Of the study was to develop and implement of stimulated calcitonin ...

Background and aims: Diabetic osteopathy in patients with type 1 diabetes (T1DM) is obvious. However, approaches to its diagnosis are still ambiguous. Thus, the aim was to study the features of serum osteo-specific parameters and dual energy X–ray absorptiometry (DXA) data in T1DM patients.Materials and methods: 157 patients with T1DM (105 women, 52 males) (mean age: 32.5 (25.5–41.6) yrs, duration of DM: 13 (7–20) yrs, age of manifestation...

Objective: The aim of this study is to evaluate the bone mineral density, hip geometry parameters and bone quality, measured by trabecular bone score (TBS) in patients with type 1 diabetes mellitus (T1DM).Materials and methods: We examined 97 patients with T1DM (28 males, 69 females, age: 31 (24.9−37.7) yrs., duration of DM: 11 (7−19.5) yrs., HbA1c: 8.6 (7.1−10) %, BMI: 23.1 (21.9−25.7) kg/m2). The control group consist...